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It is an IARC 'Group 1' carcinogen and a teratogen.[15] tobacco – Nicotiana tabacum. A legal d**g contained in tobacco leaves, which are either smoked, chewed or snuffed. It contains nicotine, which crosses the blood–brain barrier in 10–20 seconds. It mimics the action of the neurotransmitter acetylcholine at nicotinic acetylcholine receptors in the brain and the neuromuscular junction. The neuronal forms of the receptor are present both post-synaptically (involved in classical neurotransmission) and pre-synaptically, where they can influence the release of multiple neurotransmitters.[16] cannabis – Its common forms include marijuana and hashish, which are smoked or eaten. It contains at least 85 cannabinoids. The primary psychoactive component is THC, which mimics the neurotransmitter anandamide, named after the Hindu ananda, "joy, bliss, delight." The review article Campbell & Gowran (2007) states that "manipulation of the cannabinoid system offers the potential to upregulate. That’s where I found her and about of us landed up in the same city. I had already found accommodation for myself with some boys and she used to live with the girls.On many occasions, I used to help her, in case she needed it. After a year or so, I was going to go to India for my vacations and so was she. We even took our tickets together for the same dates. We had a flight from Australia to Singapore and then a 23 hrs halt in Singapore and then Singapore to Mumbai. The airlines had even given us hotel accommodations to refresh us. The flight from Australia was in the evening @ 7pm, which landed @ 1am in Singapore. We boarded the plane and she had a window seat and I had an aisle seat at the end of the aircraft. We were at the end and the plane was pretty vacant. I was enjoying my beer and we started talking about the school days and we were enjoying our time, just then, I don’t know what came to her mind, she wanted to play truth or dare.I resisted but then ended up agreeing. It.
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